FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model

BACKGROUND: Malignant mesothelioma (MM) is a very aggressive type of cancer, with a dismal prognosis and inherent resistance to chemotherapeutics. Development and evaluation of new therapeutic approaches is highly needed. Immunosuppressant FTY720, approved for multiple sclerosis treatment, has recen...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Szymiczek, Agata, Pastorino, Sandra, Larson, David, Tanji, Mika, Pellegrini, Laura, Xue, Jiaming, Li, Shuangjing, Giorgi, Carlotta, Pinton, Paolo, Takinishi, Yasutaka, Pass, Harvey I., Furuya, Hideki, Gaudino, Giovanni, Napolitano, Andrea, Carbone, Michele, Yang, Haining
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353897/
https://ncbi.nlm.nih.gov/pubmed/28298211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1158-z
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