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7α-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system

It is becoming clear that steroids can be synthesized de novo by the brain and other nervous systems. Such steroids are called neurosteroids, and de novo neurosteroidogenesis from cholesterol is a conserved property of vertebrate brains. In this study, we show that the newt brain actively produces 7...

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Detalhes bibliográficos
Main Authors: Matsunaga, Masahiro, Ukena, Kazuyoshi, Baulieu, Etienne-Emile, Tsutsui, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535386/
https://ncbi.nlm.nih.gov/pubmed/15569930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407176101
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