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RNA interference acts as a natural antiviral response to O'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae

RNA interference (RNAi) is triggered in eukaryotic organisms by double-stranded RNA (dsRNA), and it destroys any mRNA that has sequence identity with the dsRNA trigger. The RNAi pathway in Anopheles gambiae can be silenced by transfecting cells with dsRNA derived from exon sequence of the A. gambiae...

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Detalhes bibliográficos
Main Authors: Keene, Kimberly M., Foy, Brian D., Sanchez-Vargas, Irma, Beaty, Barry J., Blair, Carol D., Olson, Ken E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535383/
https://ncbi.nlm.nih.gov/pubmed/15583140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406983101
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