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RNA interference acts as a natural antiviral response to O'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae

RNA interference (RNAi) is triggered in eukaryotic organisms by double-stranded RNA (dsRNA), and it destroys any mRNA that has sequence identity with the dsRNA trigger. The RNAi pathway in Anopheles gambiae can be silenced by transfecting cells with dsRNA derived from exon sequence of the A. gambiae...

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Main Authors: Keene, Kimberly M., Foy, Brian D., Sanchez-Vargas, Irma, Beaty, Barry J., Blair, Carol D., Olson, Ken E.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC535383/
https://ncbi.nlm.nih.gov/pubmed/15583140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406983101
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