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In vitro drug testing based on contractile activity of C2C12 cells in an epigenetic drug model

Skeletal muscle tissue engineering holds great promise for pharmacological studies. Herein, we demonstrated an in vitro drug testing system using tissue-engineered skeletal muscle constructs. In response to epigenetic drugs, myotube differentiation of C2C12 myoblast cells was promoted in two-dimensi...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ikeda, Kazushi, Ito, Akira, Imada, Ryusuke, Sato, Masanori, Kawabe, Yoshinori, Kamihira, Masamichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353687/
https://ncbi.nlm.nih.gov/pubmed/28300163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44570
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