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In vitro drug testing based on contractile activity of C2C12 cells in an epigenetic drug model

Skeletal muscle tissue engineering holds great promise for pharmacological studies. Herein, we demonstrated an in vitro drug testing system using tissue-engineered skeletal muscle constructs. In response to epigenetic drugs, myotube differentiation of C2C12 myoblast cells was promoted in two-dimensi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Ikeda, Kazushi, Ito, Akira, Imada, Ryusuke, Sato, Masanori, Kawabe, Yoshinori, Kamihira, Masamichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353687/
https://ncbi.nlm.nih.gov/pubmed/28300163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44570
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