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Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

Gene expression analysis implicates an increasing number of novel genes in the brain as potential targets for the treatment of neurological and psychiatric disorders. Frequently, these genes are ubiquitously expressed in the brain and, thus, may contribute to a pathophysiological state through actio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thakker, Deepak R., Natt, Francois, Hüsken, Dieter, Maier, Rainer, Müller, Matthias, van der Putten, Herman, Hoyer, Daniel, Cryan, John F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC535368/
https://ncbi.nlm.nih.gov/pubmed/15569935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406214101
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