Inosine attenuates spontaneous activity in the rat neurogenic bladder through an A(2B) pathway

Neurogenic detrusor overactivity (NDO) is among the most challenging complications of spinal cord injury (SCI). A recent report by us demonstrated an improvement in NDO in SCI rats following chronic systemic treatment with the purine nucleoside inosine. The objective of this study was to investigate...

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Udgivet i:Sci Rep
Main Authors: Doyle, Claire, Cristofaro, Vivian, Sack, Bryan S., Lukianov, Stefan N., Schäfer, Mattias, Chung, Yeun Goo, Sullivan, Maryrose P., Adam, Rosalyn M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353659/
https://ncbi.nlm.nih.gov/pubmed/28294142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44416
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