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Structural basis of activity and allosteric control of diguanylate cyclase

Recent discoveries suggest that a novel second messenger, bis-(3′→5′)-cyclic di-GMP (c-diGMP), is extensively used by bacteria to control multicellular behavior. Condensation of two GTP to the dinucleotide is catalyzed by the widely distributed diguanylate cyclase (DGC or GGDEF) domain that occurs i...

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Detalhes bibliográficos
Main Authors: Chan, Carmen, Paul, Ralf, Samoray, Dietrich, Amiot, Nicolas C., Giese, Bernd, Jenal, Urs, Schirmer, Tilman
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535365/
https://ncbi.nlm.nih.gov/pubmed/15569936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406134101
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