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Role of purinergic signaling in experimental pneumococcal meningitis
Excessive neutrophilic inflammation contributes to brain pathology and adverse outcome in pneumococcal meningitis (PM). Recently, we identified the NLRP3 inflammasome/interleukin (IL)-1β pathway as a key driver of inflammation in PM. A critical membrane receptor for NLRP3 inflammasome activation is...
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Publicat a: | Sci Rep |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Nature Publishing Group
2017
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5353597/ https://ncbi.nlm.nih.gov/pubmed/28300164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44625 |
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