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Restricted inactivation of serum response factor to the cardiovascular system

Serum response factor (SRF) directs programs of gene expression linked to growth and muscle differentiation. To investigate the role of SRF in cardiovascular development, we generated mice in which SRF is knocked out in >80% of cardiomyocytes and >50% of vascular smooth muscle cells (SMC) thro...

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Detalhes bibliográficos
Main Authors: Miano, Joseph M., Ramanan, Narendrakumar, Georger, Mary A., de Mesy Bentley, Karen L., Emerson, Rachael L., Balza, Robert O., Xiao, Qi, Weiler, Hartmut, Ginty, David D., Misra, Ravi P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC535359/
https://ncbi.nlm.nih.gov/pubmed/15569937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406041101
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