miR-34a mediates oxaliplatin resistance of colorectal cancer cells by inhibiting macroautophagy via transforming growth factor-β/Smad4 pathway

AIM: To investigate whether microRNA (miR)-34a mediates oxaliplatin (OXA) resistance of colorectal cancer (CRC) cells by inhibiting macroautophagy via the transforming growth factor (TGF)-β/Smad4 pathway. METHODS: miR-34a expression levels were detected in CRC tissues and CRC cell lines by quantitat...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Sun, Chen, Wang, Fu-Jing, Zhang, Hao-Gang, Xu, Xun-Zheng, Jia, Rui-Chun, Yao, Lei, Qiao, Peng-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2017
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352922/
https://ncbi.nlm.nih.gov/pubmed/28348487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i10.1816
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