Combination of ICP-MS, capillary electrophoresis, and their hyphenation for probing Ru(III) metallodrug–DNA interactions

Determination of the DNA-binding reactivity and affinity is an important part of a successful program for the selection of metallodrug candidates. For such assaying, a range of complementary analytical techniques was proposed and tested here using one of few anticancer metal-based drugs that are cur...

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Dettagli Bibliografici
Pubblicato in:Anal Bioanal Chem
Autori principali: Foteeva, Lidia S., Matczuk, Magdalena, Pawlak, Katarzyna, Aleksenko, Svetlana S., Nosenko, Sergey V., Karandashev, Vasily K., Jarosz, Maciej, Timerbaev, Andrei R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352744/
https://ncbi.nlm.nih.gov/pubmed/28116493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-017-0186-0
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