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Preclinical assesement of survivin and XIAP as prognostic biomarkers and therapeutic targets in gastroenteropancreatic neuroendocrine neoplasia

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) represent a rare and heterogenous tumor entity. Importantly, the highly proliferative subgroup of neuroendocrine carcinoma (GEP-NEC) is characterized by high resistance to conventional chemotherapy. Consequently, there is an urgent need to id...

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Pubblicato in:Oncotarget
Autori principali: Dizdar, Levent, Oesterwind, Kira A., Riemer, Jasmin C., Werner, Thomas A., Mersch, Sabrina, Möhlendick, Birte, Schütte, Sina C., Verde, Pablo E., Raba, Katharina, Topp, Stefan A., Stoecklein, Nikolas H., Esposito, Irene, Knoefel, Wolfram T., Krieg, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352407/
https://ncbi.nlm.nih.gov/pubmed/28039474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14207
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