Aberrant promoter methylation of hOGG1 may be associated with increased risk of non-small cell lung cancer

DNA methylation may epigenetically inactivate tumor suppressor genes in NSCLC. As the human 8-oxoguanine DNA glycosylase (hOGG1) gene promoter is frequently methylated in NSCLC, we evaluated whether genetic or epigenetic alterations of hOGG1 are associated with increased risk of non-small cell lung...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qin, Hualong, Zhu, Jianjie, Zeng, Yuanyuan, Du, Wenwen, Shen, Dan, Lei, Zhe, Qian, Qian, Huang, Jian-an, Liu, Zeyi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352404/
https://ncbi.nlm.nih.gov/pubmed/28039450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14177
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