Paeoniflorin ameliorates interferon-alpha-induced neuroinflammation and depressive-like behaviors in mice

Long-term treatment with high-dose Interferon-alpha (IFN-α) has resulted in depression in 30–50% of the patients. Paeoniflorin may ameliorate the IFN-α-induced depression; however, the underlying mechanism is less studied. Here, we investigated the prophylactic antidepressant and anti-neuroinflammat...

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Udgivet i:Oncotarget
Main Authors: Li, Jianwei, Huang, Shaohui, Huang, Weiliang, Wang, Wanshan, Wen, Ge, Gao, Lei, Fu, Xiuqiong, Wang, Mengmeng, Liang, Weihai, Kwan, Hiu Yee, Zhao, Xiaoshan, Lv, Zhiping
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352399/
https://ncbi.nlm.nih.gov/pubmed/28030814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14160
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