BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers

Here, BTG1 overexpression inhibited proliferation, induced differentiation, autophagy, and apoptosis in colorectal cancer cells (p(2) arrest might be related to Cyclin B1 and Cdc25B hypoexpression in HCT-15 transfectants, while G(1) arrest in HCT-116 transfectants overexpressing p21 and p27. BTG1 ov...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhao, Shuang, Chen, Shu-rui, Yang, Xue-feng, Shen, Dao-fu, Takano, Yasuo, Su, Rong-jian, Zheng, Hua-chuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352338/
https://ncbi.nlm.nih.gov/pubmed/27447746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10649
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