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Fluorescence Turn-On Sensing of DNA Duplex Formation by a Tricyclic Cytidine Analogue

Most fluorescent nucleoside analogues are quenched when base stacked and some maintain their brightness, but there has been little progress toward developing nucleoside analogues that markedly increase their fluorescence upon duplex formation. Here, we report on the design and synthesis of a new tri...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Burns, Dillon D., Teppang, Kristine L., Lee, Raymond W., Lokensgard, Melissa E., Purse, Byron W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352299/
https://ncbi.nlm.nih.gov/pubmed/28080035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10410
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