A potential in situ gel formulation loaded with novel fabricated poly(lactide-co-glycolide) nanoparticles for enhancing and sustaining the ophthalmic delivery of ketoconazole

Oral ketoconazole therapy is commonly associated with serious hepatotoxicity. Improving ocular drug delivery could be sufficient to treat eye fungal infections. The purpose of this study was to develop optimized ketoconazole poly(lactide-co-glycolide) nanoparticles (NPs) with subsequent loading into...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Ahmed, Tarek Abdelnapy, Aljaeid, Bader M
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352245/
https://ncbi.nlm.nih.gov/pubmed/28331311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S131850
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