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Discovering sparse transcription factor codes for cell states and state transitions during development

Computational analysis of gene expression to determine both the sequence of lineage choices made by multipotent cells and to identify the genes influencing these decisions is challenging. Here we discover a pattern in the expression levels of a sparse subset of genes among cell types in B- and T-cel...

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Publicat a:eLife
Autors principals: Furchtgott, Leon A, Melton, Samuel, Menon, Vilas, Ramanathan, Sharad
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352226/
https://ncbi.nlm.nih.gov/pubmed/28296636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20488
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