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Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire(−/−) mice
Autoimmune regulator (Aire) is essential in the perinatal period to prevent the multiorgan autoimmunity. Here we show that Aire-regulated single positive thymocyte trafficking in neonatal period is critical for thymic egress. Reduced thymic emigration was found in Aire(−/−) mice during neonatal peri...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352200/ https://ncbi.nlm.nih.gov/pubmed/27965471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13909 |
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