Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth

The oncogenic potential of the transcriptional repressor Bcl-6 (B-cell lymphoma 6) was originally discovered in non-Hodgkin patients and the soluble Bcl-6 inhibitor 79-6 was developed to treat diffuse large B-cell lymphomas with aberrant Bcl-6 expression. Since we found Bcl-6 and its co-repressor BC...

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Udgivet i:Oncotarget
Main Authors: Buchberger, Elisabeth, Payrhuber, Dietmar, Harchi, Miriam El, Zagrapan, Branislav, Scheuba, Katharina, Zommer, Anna, Bugyik, Edina, Dome, Balazs, Kral, Julia Barbara, Schrottmaier, Waltraud Cornelia, Schabbauer, Gernot, Petzelbauer, Peter, Gröger, Marion, Bilban, Martin, Brostjan, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352177/
https://ncbi.nlm.nih.gov/pubmed/27880939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13477
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