Загрузка...
Development of venetoclax for therapy of lymphoid malignancies
B-cell lymphoma-2 (BCL-2) family dysfunction and impairment of apoptosis are common in most B-cell lymphoid malignancies. Venetoclax (Venclexta™, formerly ABT-199, GDC-0199) is a highly selective BCL-2 inhibitor, which mimics its BCL-2 homology 3-domain to induce apoptosis. It was approved for treat...
Сохранить в:
| Опубликовано в: : | Drug Des Devel Ther |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Dove Medical Press
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352161/ https://ncbi.nlm.nih.gov/pubmed/28331288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S109325 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|