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Deacetylation of sialic acid by esterases potentiates pneumococcal neuraminidase activity for mucin utilization, colonization and virulence

Pneumococcal neuraminidase is a key enzyme for sequential deglycosylation of host glycans, and plays an important role in host survival, colonization, and pathogenesis of infections caused by Streptococcus pneumoniae. One of the factors that can affect the activity of neuraminidase is the amount and...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kahya, Hasan F., Andrew, Peter W., Yesilkaya, Hasan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352144/
https://ncbi.nlm.nih.gov/pubmed/28257499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006263
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