Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

Culture of cancerous cells in standard monolayer conditions poorly mirrors growth in three-dimensional architectures typically observed in a wide majority of cancers of different histological origin. Multicellular tumor spheroid (MCTS) culture models were developed to mimic these features. However,...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Däster, Silvio, Amatruda, Nunzia, Calabrese, Diego, Ivanek, Robert, Turrini, Eleonora, Droeser, Raoul A., Zajac, Paul, Fimognari, Carmela, Spagnoli, Giulio C., Iezzi, Giandomenica, Mele, Valentina, Muraro, Manuele G.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352092/
https://ncbi.nlm.nih.gov/pubmed/27965457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13857
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