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Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment
Culture of cancerous cells in standard monolayer conditions poorly mirrors growth in three-dimensional architectures typically observed in a wide majority of cancers of different histological origin. Multicellular tumor spheroid (MCTS) culture models were developed to mimic these features. However,...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352092/ https://ncbi.nlm.nih.gov/pubmed/27965457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13857 |
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