DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients

Tumor-cell-secreted extracellular vesicles (EVs) can cross the disrupted blood-brain barrier (BBB) into the bloodstream. However, in certain gliomas, the BBB remains intact, which might limit EVs release. To evaluate the ability of tumor-derived EVs to cross the BBB, we used an orthotopic xenotransp...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: García-Romero, Noemí, Carrión-Navarro, Josefa, Esteban-Rubio, Susana, Lázaro-Ibáñez, Elisa, Peris-Celda, María, Alonso, Marta M., Guzmán-De-Villoria, Juan, Fernández-Carballal, Carlos, de Mendivil, Ana Ortiz, García-Duque, Sara, Escobedo-Lucea, Carmen, Prat-Acín, Ricardo, Belda-Iniesta, Cristóbal, Ayuso-Sacido, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352065/
https://ncbi.nlm.nih.gov/pubmed/27902458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13635
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