Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts

Acto-myosin contractility in carcinoma-associated fibroblasts leads to assembly of the tumor extracellular matrix. The pro-inflammatory cytokine LIF governs fibroblast activation in cancer by regulating the myosin light chain 2 activity. So far, however, how LIF mediates cytoskeleton contractility r...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bonan, Stephanie, Albrengues, Jean, Grasset, Eloise, Kuzet, Sanya-Eduarda, Nottet, Nicolas, Bourget, Isabelle, Bertero, Thomas, Mari, Bernard, Meneguzzi, Guerrino, Gaggioli, Cedric
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352056/
https://ncbi.nlm.nih.gov/pubmed/27901489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13610
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