Genetic variation in the vitamin D pathway CYP2R1 gene predicts sustained HBeAg seroconversion in chronic hepatitis B patients treated with pegylated interferon: A multicenter study

Evidence of a role of vitamin D in the immune system is increasing. Low serum vitamin D is associated with increased hepatitis B virus replication. Genome-wide association study (GWAS) data has revealed a number of the single nucleotide polymorphisms (SNPs) within the vitamin D synthetic pathway tha...

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Publié dans:PLoS One
Auteurs principaux: Thanapirom, Kessarin, Suksawatamnuay, Sirinporn, Sukeepaisarnjareon, Wattana, Tanwandee, Tawesak, Charatcharoenwitthaya, Phunchai, Thongsawat, Satawat, Leerapun, Apinya, Piratvisuth, Teerha, Boonsirichan, Rattana, Bunchorntavakul, Chalermrat, Pattanasirigool, Chaowalit, Pornthisarn, Bubpha, Tantipanichtheerakul, Supot, Sripariwuth, Ekawee, Jeamsripong, Woramon, Sanpajit, Teeranan, Poovorawan, Yong, Komolmit, Piyawat
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351865/
https://ncbi.nlm.nih.gov/pubmed/28296915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173263
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