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Perinatal high methyl donor alters gene expression in IGF system in male offspring without altering DNA methylation

AIM: To investigate the effect of a protein restriction and a supplementation with methyl donor nutrients during fetal and early postnatal life on the expression and epigenetic state of imprinted genes from the IGF system. MATERIALS & METHODS: Pregnant female rats were fed a protein-restricted d...

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Detalhes bibliográficos
Publicado no:Future Sci OA
Main Authors: Amarger, Valérie, Giudicelli, Fanny, Pagniez, Anthony, Parnet, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351714/
https://ncbi.nlm.nih.gov/pubmed/28344827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fsoa-2016-0077
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