Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer

Cyclooxygenase-2 (COX-2) and its primary enzymatic product, prostaglandin E2 (PGE2), are associated with a poor prognosis in breast cancer. In order to elucidate the factors contributing to intratumoral PGE(2) levels, we evaluated the expression of COX-2/PGE(2) pathway members MRP4, the prostaglandi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kochel, Tyler J, Reader, Jocelyn C, Ma, Xinrong, Kundu, Namita, Fulton, Amy M
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351651/
https://ncbi.nlm.nih.gov/pubmed/28029661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14145
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