PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

Despite improvement of therapeutic treatments for breast cancer, the development of brain metastases has become a major limitation to life expectancy for many patients. Brain metastases show very commonly alterations in EGFR and HER2 driven pathways, of which PTEN is an important regulator. Here, we...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Hohensee, Ina, Chuang, Han-Ning, Grottke, Astrid, Werner, Stefan, Schulte, Alexander, Horn, Stefan, Lamszus, Katrin, Bartkowiak, Kai, Witzel, Isabell, Westphal, Manfred, Matschke, Jakob, Glatzel, Markus, Jücker, Manfred, Pukrop, Tobias, Pantel, Klaus, Wikman, Harriet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351620/
https://ncbi.nlm.nih.gov/pubmed/28008153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14047
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