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Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle

Myostatin, a member of the transforming growth factor-beta superfamily, is a negative regulator of skeletal muscle growth and development. Myostatin inhibition leads to increased skeletal muscle mass in mammals; hence, myostatin is considered a potential therapeutic target for skeletal muscle wastin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hitachi, Keisuke, Tsuchida, Kunihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351603/
https://ncbi.nlm.nih.gov/pubmed/27992376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13966
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