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Building confidence in quantitative systems pharmacology models: An engineer's guide to exploring the rationale in model design and development

This tutorial promotes good practice for exploring the rationale of systems pharmacology models. A safety systems engineering inspired notation approach provides much needed rigor and transparency in development and application of models for therapeutic discovery and design of intervention strategie...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Timmis, J, Alden, K, Andrews, P, Clark, E, Nellis, A, Naylor, B, Coles, M, Kaye, P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351409/
https://ncbi.nlm.nih.gov/pubmed/27863172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12157
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