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Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination.

Retroviruses contain two complete viral genomic RNAs in each virion. A system to study in a single round of replication the products of virions with two different genomic RNAs was established. A spleen necrosis virus-based splicing vector containing both the neomycin-resistance gene (neo) and the hy...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hu, W S, Temin, H M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53514/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1556
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