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TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo

The aim of the present study was to investigate the radiosensitization effect of triciribine (TCN) on human esophageal squamous cell carcinoma (ESCC) in normoxia or hypoxia and its mechanism. The cytotoxicity and radiosensitization mechanism of TCN were investigated by Cell Counting Kit 8, clonogeni...

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Detaylı Bibliyografya
Yayımlandı:Oncol Lett
Asıl Yazarlar: Guo, Qing, He, Jia, Shen, Feng, Zhang, Wei, Yang, Xi, Zhang, Chi, Zhang, Qu, Huang, Jun-Xing, Wu, Zheng-Dong, Sun, Xin-Chen, Dai, Sheng-Bin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351392/
https://ncbi.nlm.nih.gov/pubmed/28356983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5515
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