TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo

The aim of the present study was to investigate the radiosensitization effect of triciribine (TCN) on human esophageal squamous cell carcinoma (ESCC) in normoxia or hypoxia and its mechanism. The cytotoxicity and radiosensitization mechanism of TCN were investigated by Cell Counting Kit 8, clonogeni...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Guo, Qing, He, Jia, Shen, Feng, Zhang, Wei, Yang, Xi, Zhang, Chi, Zhang, Qu, Huang, Jun-Xing, Wu, Zheng-Dong, Sun, Xin-Chen, Dai, Sheng-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351392/
https://ncbi.nlm.nih.gov/pubmed/28356983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5515
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