Autologous c‐Kit+ Mesenchymal Stem Cell Injections Provide Superior Therapeutic Benefit as Compared to c‐Kit+ Cardiac‐Derived Stem Cells in a Feline Model of Isoproterenol‐Induced Cardiomyopathy

BACKGROUND: Cardiac‐ (CSC) and mesenchymal‐derived (MSC) CD117+ isolated stem cells improve cardiac function after injury. However, no study has compared the therapeutic benefit of these cells when used autologously. METHODS: MSCs and CSCs were isolated on day 0. Cardiomyopathy was induced (day 28)...

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Bibliografiske detaljer
Udgivet i:Clin Transl Sci
Main Authors: Taghavi, Sharven, Sharp, Thomas E., Duran, Jason M., Makarewich, Catherine A., Berretta, Remus M., Starosta, Tim, Kubo, Hajime, Barbe, Mary, Houser, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Original Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351102/
https://ncbi.nlm.nih.gov/pubmed/25684108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12251
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