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Phase I Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis

There is a significant unmet need for safe and effective anti‐inflammatory treatment for cystic fibrosis. The aim of this study was to evaluate the safety of acebilustat, a leukotriene A4 hydrolase inhibitor, and its effect on inflammation biomarkers in patients with cystic fibrosis. Seventeen patie...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Elborn, JS, Horsley, A, MacGregor, G, Bilton, D, Grosswald, R, Ahuja, S, Springman, EB
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351012/
https://ncbi.nlm.nih.gov/pubmed/27806191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12428
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