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Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing
Using the proteomic tandem affinity purification (TAP) method, we have purified the Saccharomyces cerevisie U2 snRNP-associated splicing factors SF3a and SF3b. While SF3a purification revealed only the expected subunits Prp9p, Prp11p and Prp21p, yeast SF3b was found to contain only six subunits, inc...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535094/ https://ncbi.nlm.nih.gov/pubmed/15565172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600482 |
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