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Inhibition of Protein 4.1 R and NuMA Interaction by Mutagenization of Their Binding‐Sites Abrogates Nuclear Localization of 4.1 R

Protein 4.1R(4.1R) is a multifunctional structural protein recently implicated in nuclear assembly and cell division. We earlier demonstrated that 4.1R forms a multiprotein complex with mitotic spindle and spindle pole organizing proteins, such as NuMA, dynein, and dynactin, by binding to residues 1...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Mattagajasingh, Subhendra N., Huang, Shu‐Ching, Benz, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350677/
https://ncbi.nlm.nih.gov/pubmed/20443879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00087.x
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