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EphB6-null mutation results in compromised T cell function

So far, there is very limited knowledge about the role of Eph kinases, the largest family of receptor tyrosine kinases, in the immune system. Here, using EphB6(–/–) mice, we demonstrated that in vitro and in vivo T cell responses such as lymphokine secretion, proliferation, and the development of de...

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Autors principals: Luo, Hongyu, Yu, Guang, Tremblay, Johanne, Wu, Jiangping
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC535066/
https://ncbi.nlm.nih.gov/pubmed/15599401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421846
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