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Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3

The present study examines the role of Pyk2 in acid regulation of sodium/hydrogen exchanger 3 (NHE3) activity in OKP cells, a kidney proximal tubule epithelial cell line. Incubation of OKP cells in acid media caused a transient increase in Pyk2 phosphorylation that peaked at 30 seconds and increased...

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Bibliografiske detaljer
Main Authors: Li, Shaoying, Sato, Soichiro, Yang, Xiaojing, Preisig, Patricia A., Alpern, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC535061/
https://ncbi.nlm.nih.gov/pubmed/15599403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418046
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