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A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage

DNA double strand breaks (DSBs) are generally repaired through nonhomologous end joining or homologous recombination. In this issue, Liu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607031) report that the conserved scaffold protein TOPBP1(Dpb11) provides binding sites for both pro- an...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Shimada, Kenji, Gasser, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350523/
https://ncbi.nlm.nih.gov/pubmed/28235945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201701038
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