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Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by Coilin Downregulation and the Accumulation of Cajal Bodies in Nucleoli

Cajal bodies (CBs) are important compartments containing accumulated proteins that preferentially regulate RNA-related nuclear events, including splicing. Here, we studied the nuclear distribution pattern of CBs in neurogenesis. In adult brains, coilin was present at a high density, but CB formation...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Krejčí, Jana, Legartová, Soňa, Bártová, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350323/
https://ncbi.nlm.nih.gov/pubmed/28337219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1021240
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