Molecular Mechanism for the Regulation of Microcystin Toxicity to Protein Phosphatase 1 by Glutathione Conjugation Pathway

Glutathione (GSH) conjugation was an important pathway to regulate the toxicity of microcystins (MCs) targeted to protein phosphatases. To explore the specific molecular mechanism for GSH detoxification, two typical MC-GSHs (derived from MCLR and MCRR) were synthesized, prepared, and purified accord...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zong, Wansong, Wang, Xiaoning, Du, Yonggang, Zhang, Shuhan, Zhang, Ying, Teng, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350311/
https://ncbi.nlm.nih.gov/pubmed/28337461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9676504
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