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Efficacy of Resistance to Francisella Imparted by ITY/NRAMP/SLC11A1 Depends on Route of Infection

Natural resistance-associated macrophage protein (NRAMP) encoded by the Slc11a1 gene is a membrane-associated transporter of divalent metal ions. Murine Slc11a1 has two known alleles, a functional Slc11a1(Gly169), which is found in DBA2/J, NOD/LtJ, and 129p3/J and related mouse strains, and a non-fu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Powell, Daniel A., Frelinger, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350118/
https://ncbi.nlm.nih.gov/pubmed/28360906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00206
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