A regulatory loop involving miR-29c and Sp1 elevates the TGF-β1 mediated epithelial-to-mesenchymal transition in lung cancer

Specificity protein1 (Sp1) is required for TGF-β-induced epithelial-to-mesenchymal transition (EMT) which has been demonstrated to aggravate the progression of cancer including lung cancer. microRNA-29c (miR-29c) is identified to inhibit EMT, but the correlation between miR-29c and Sp1 in human lung...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Hai-wei, Wang, En-wen, Li, Li-xian, Yi, Shou-hui, Li, Lu-chun, Xu, Fa-liang, Wang, Dong-lin, Wu, Yong-zhong, Nian, Wei-qi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349884/
https://ncbi.nlm.nih.gov/pubmed/27829234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13137
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