Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice

Nonalcoholic fatty liver disease (NAFLD) is widespread in adults and children. Early exposure to maternal obesity or Western-style diet (WD) increases steatosis and oxidative stress in fetal liver and is associated with lifetime disease risk in the offspring. Pyrroloquinoline quinone (PQQ) is a natu...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Jonscher, Karen R., Stewart, Michael S., Alfonso-Garcia, Alba, DeFelice, Brian C., Wang, Xiaoxin X., Luo, Yuhuan, Levi, Moshe, Heerwagen, Margaret J. R., Janssen, Rachel C., de la Houssaye, Becky A., Wiitala, Ellen, Florey, Garrett, Jonscher, Raleigh L., Potma, Eric O., Fiehn, Oliver, Friedman, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349805/
https://ncbi.nlm.nih.gov/pubmed/28007783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600906R
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