Role of cardiotrophin-1 in the regulation of metabolic circadian rhythms and adipose core clock genes in mice and characterization of 24-h circulating CT-1 profiles in normal-weight and overweight/obese subjects

Cardiotrophin (CT)-1 is a regulator of glucose and lipid homeostasis. In the present study, we analyzed whether CT-1 also acts to peripherally regulate metabolic rhythms and adipose tissue core clock genes in mice. Moreover, the circadian pattern of plasma CT-1 levels was evaluated in normal-weight...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: López-Yoldi, Miguel, Stanhope, Kimber L., Garaulet, Marta, Chen, X. Guoxia, Marcos-Gómez, Beatriz, Carrasco-Benso, María Paz, Santa Maria, Eva M., Escoté, Xavier, Lee, Vivien, Nunez, Marinelle V., Medici, Valentina, Martínez-Ansó, Eduardo, Sáinz, Neira, Huerta, Ana E., Laiglesia, Laura M., Prieto, Jesús, Martínez, J. Alfredo, Bustos, Matilde, Havel, Peter J., Moreno-Aliaga, Maria J.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349803/
https://ncbi.nlm.nih.gov/pubmed/28096235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600396RR
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