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Identification of Elongated Primary Cilia with Impaired Mechanotransduction in Idiopathic Scoliosis Patients

The primary cilium is an outward projecting antenna-like organelle with an important role in bone mechanotransduction. The capacity to sense mechanical stimuli can affect important cellular and molecular aspects of bone tissue. Idiopathic scoliosis (IS) is a complex pediatric disease of unknown caus...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Oliazadeh, Niaz, Gorman, Kristen F., Eveleigh, Robert, Bourque, Guillaume, Moreau, Alain
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349607/
https://ncbi.nlm.nih.gov/pubmed/28290481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44260
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