Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer’s Disease

Neuroimaging genetics is an emerging field that aims to identify the associations between genetic variants (e.g., single nucleotide polymorphisms (SNPs)) and quantitative traits (QTs) such as brain imaging phenotypes. In recent studies, in order to detect complex multi-SNP-multi-QT associations, bi-...

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Vydáno v:Sci Rep
Hlavní autoři: Hao, Xiaoke, Li, Chanxiu, Du, Lei, Yao, Xiaohui, Yan, Jingwen, Risacher, Shannon L., Saykin, Andrew J., Shen, Li, Zhang, Daoqiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349597/
https://ncbi.nlm.nih.gov/pubmed/28291242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44272
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