Extracellular matrix and α(5)β(1) integrin signaling control the maintenance of bone formation capacity by human adipose-derived stromal cells

Stromal vascular fraction (SVF) cells of human adipose tissue have the capacity to generate osteogenic grafts with intrinsic vasculogenic properties. However, adipose-derived stromal/stem cells (ASC), even after minimal monolayer expansion, display poor osteogenic capacity in vivo. We investigated w...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Di Maggio, Nunzia, Martella, Elisa, Frismantiene, Agne, Resink, Therese J., Schreiner, Simone, Lucarelli, Enrico, Jaquiery, Claude, Schaefer, Dirk J., Martin, Ivan, Scherberich, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349595/
https://ncbi.nlm.nih.gov/pubmed/28290502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44398
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